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Elevated BICD2 DNA methylation in blood of major depressive disorder patients and reduction of depressive-like behaviors in hippocampal Bicd2-knockdown mice
Major depressive disorder (MDD) is a prevalent and devastating mental illness. To date, the diagnosis of MDD is largely dependent on clinical interviews and questionnaires and still lacks a reliable biomarker. DNA methylation has a stable and reversible nature and is likely associated with the cours...
Autores principales: | Xiu, Jianbo, Li, Jiayu, Liu, Zeyue, Wei, Hui, Zhu, Caiyun, Han, Rongrong, Liu, Zijing, Zhu, Wanwan, Shen, Yan, Xu, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335189/ https://www.ncbi.nlm.nih.gov/pubmed/35858435 http://dx.doi.org/10.1073/pnas.2201967119 |
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