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Antibody-mediated blockade for galectin-3 binding protein in tumor secretome abrogates PDAC metastasis

The major challenges in pancreatic ductal adenocarcinoma (PDAC) management are local or distant metastasis and limited targeted therapeutics to prevent it. To identify a druggable target in tumor secretome and to explore its therapeutic intervention, we performed a liquid chromatography–tandem mass...

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Detalles Bibliográficos
Autores principales: Choi, Yeon-Sook, Kim, Myung Ji, Choi, Eun A., Kim, Sinae, Lee, Eun ji, Park, Min Ji, Kim, Mi-Ju, Kim, Yeon Wook, Ahn, Hee-Sung, Jung, Jae Yun, Jang, Gayoung, Kim, Yongsub, Kim, Hyori, Kim, Kyunggon, Kim, Jin Young, Hong, Seung-Mo, Kim, Song Cheol, Chang, Suhwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335190/
https://www.ncbi.nlm.nih.gov/pubmed/35858411
http://dx.doi.org/10.1073/pnas.2119048119