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Phosphorylation of Arl4A/D promotes their binding by the HYPK chaperone for their stable recruitment to the plasma membrane

The Arl4 small GTPases participate in a variety of cellular events, including cytoskeleton remodeling, vesicle trafficking, cell migration, and neuronal development. Whereas small GTPases are typically regulated by their GTPase cycle, Arl4 proteins have been found to act independent of this canonica...

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Detalles Bibliográficos
Autores principales: Lin, Ming-Chieh, Yu, Chia-Jung, Lee, Fang-Jen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335210/
https://www.ncbi.nlm.nih.gov/pubmed/35857868
http://dx.doi.org/10.1073/pnas.2207414119