Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories

Human infections with methicillin-resistant Staphylococcus aureus (MRSA) are commonly treated with vancomycin, and strains with decreased susceptibility, designated as vancomycin-intermediate S. aureus (VISA), are associated with treatment failure. Here, we profiled the phenotypic, mutational, and t...

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Detalles Bibliográficos
Autores principales: Fait, Anaëlle, Seif, Yara, Mikkelsen, Kasper, Poudel, Saugat, Wells, Jerry M., Palsson, Bernhard O., Ingmer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335240/
https://www.ncbi.nlm.nih.gov/pubmed/35858453
http://dx.doi.org/10.1073/pnas.2118262119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335240/
https://www.ncbi.nlm.nih.gov/pubmed/35858453
http://dx.doi.org/10.1073/pnas.2118262119

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