EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus–infected B cells

Epstein-Barr virus (EBV) is a human tumor virus which preferentially infects resting human B cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent protein EBV nuclear antigen 2 (EBNA2) is essential for B cell activation and immortalization; it targets and binds...

Descripción completa

Detalles Bibliográficos
Autores principales: Beer, Sophie, Wange, Lucas E., Zhang, Xiang, Kuklik-Roos, Cornelia, Enard, Wolfgang, Hammerschmidt, Wolfgang, Scialdone, Antonio, Kempkes, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335265/
https://www.ncbi.nlm.nih.gov/pubmed/35857872
http://dx.doi.org/10.1073/pnas.2200512119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335265/
https://www.ncbi.nlm.nih.gov/pubmed/35857872
http://dx.doi.org/10.1073/pnas.2200512119

Ejemplares similares