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Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors
Transporters belonging to the Resistance-Nodulation-cell Division (RND) superfamily of proteins such as Mycobacterium tuberculosis MmpL3 and its analogs are the focus of intense investigations due to their importance in the physiology of Corynebacterium–Mycobacterium–Nocardia species and antimycobac...
Autores principales: | Stevens, Casey M., Babii, Svitlana O., Pandya, Amitkumar N., Li, Wei, Li, Yupeng, Mehla, Jitender, Scott, Robyn, Hegde, Pooja, Prathipati, Pavan K., Acharya, Atanu, Liu, Jinchan, Gumbart, James C., North, Jeffrey, Jackson, Mary, Zgurskaya, Helen I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335285/ https://www.ncbi.nlm.nih.gov/pubmed/35858440 http://dx.doi.org/10.1073/pnas.2113963119 |
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