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Superresolution microscopy localizes endogenous Dvl2 to Wnt signaling-responsive biomolecular condensates

During organismal development, homeostasis, and disease, Dishevelled (Dvl) proteins act as key signaling factors in beta-catenin–dependent and beta-catenin–independent Wnt pathways. While their importance for signal transmission has been genetically demonstrated in many organisms, our mechanistic un...

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Detalles Bibliográficos
Autores principales: Schubert, Antonia, Voloshanenko, Oksana, Ragaller, Franziska, Gmach, Philipp, Kranz, Dominique, Scheeder, Christian, Miersch, Thilo, Schulz, Matthias, Trümper, Lorenz, Binder, Claudia, Lampe, Marko, Engel, Ulrike, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335300/
https://www.ncbi.nlm.nih.gov/pubmed/35867833
http://dx.doi.org/10.1073/pnas.2122476119