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Pervasive transcription enhances the accessibility of H-NS–silenced promoters and generates bistability in Salmonella virulence gene expression

In Escherichia coli and Salmonella, many genes silenced by the nucleoid structuring protein H-NS are activated upon inhibiting Rho-dependent transcription termination. This response is poorly understood and difficult to reconcile with the view that H-NS acts mainly by blocking transcription initiati...

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Detalles Bibliográficos
Autores principales: Figueroa-Bossi, Nara, Sánchez-Romero, María Antonia, Kerboriou, Patricia, Naquin, Delphine, Mendes, Clara, Bouloc, Philippe, Casadesús, Josep, Bossi, Lionello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335307/
https://www.ncbi.nlm.nih.gov/pubmed/35858437
http://dx.doi.org/10.1073/pnas.2203011119