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LOCOM: A logistic regression model for testing differential abundance in compositional microbiome data with false discovery rate control
Compositional analysis is based on the premise that a relatively small proportion of taxa are differentially abundant, while the ratios of the relative abundances of the remaining taxa remain unchanged. Most existing methods use log-transformed data, but log-transformation of data with pervasive zer...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335309/ https://www.ncbi.nlm.nih.gov/pubmed/35867822 http://dx.doi.org/10.1073/pnas.2122788119 |