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MiR-550a-3p restores damaged vascular smooth muscle cells by inhibiting thrombomodulin in an in vitro atherosclerosis model

Thrombomodulin (TM) is involved in the pathological process of atherosclerosis; however, the underlying mechanism remains unclear. Oxidised low-density lipoprotein (Ox-LDL; 100 μg/mL) was used to induce human vascular smooth muscle cells (HVSMCs) into a stable atherosclerotic cell model. The express...

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Detalles Bibliográficos
Autores principales: Chen, Shiyuan, Zhang, Longfei, Feng, Benchi, Wang, Wei, Liu, Delang, Zhao, Xinyu, Yu, Chaowen, Wang, Xiaogao, Gao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335314/
https://www.ncbi.nlm.nih.gov/pubmed/35855629
http://dx.doi.org/10.4081/ejh.2022.3429