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Thioester synthesis by a designed nickel enzyme models prebiotic energy conversion

The formation of carbon–carbon bonds from prebiotic precursors such as carbon dioxide represents the foundation of all primordial life processes. In extant organisms, this reaction is carried out by the carbon monoxide dehydrogenase (CODH)/acetyl coenzyme A synthase (ACS) enzyme, which performs the...

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Detalles Bibliográficos
Autores principales: Manesis, Anastasia C., Yerbulekova, Alina, Shearer, Jason, Shafaat, Hannah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335327/
https://www.ncbi.nlm.nih.gov/pubmed/35858422
http://dx.doi.org/10.1073/pnas.2123022119