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The global succinylation of SARS-CoV-2–infected host cells reveals drug targets

SARS-CoV-2, the causative agent of the COVID-19 pandemic, undergoes continuous evolution, highlighting an urgent need for development of novel antiviral therapies. Here we show a quantitative mass spectrometry-based succinylproteomics analysis of SARS-CoV-2 infection in Caco-2 cells, revealing drama...

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Detalles Bibliográficos
Autores principales: Liu, Quan, Wang, Heming, Zhang, He, Sui, Liyan, Li, Letian, Xu, Wang, Du, Shouwen, Hao, Pengfei, Jiang, Yuhang, Chen, Jing, Qu, Xiaoyun, Tian, Mingyao, Zhao, Yinghua, Guo, Xuerui, Wang, Xingye, Song, Wu, Song, Guangqi, Wei, Zhengkai, Hou, Zhijun, Wang, Guoqing, Sun, Minhua, Li, Xiao, Lu, Huijun, Zhuang, Xinyu, Jin, Ningyi, Zhao, Yicheng, Li, Chang, Liao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335334/
https://www.ncbi.nlm.nih.gov/pubmed/35858407
http://dx.doi.org/10.1073/pnas.2123065119