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Toward a Topology-Based Therapeutic Design of Membrane Proteins: Validation of NaPi2b Topology in Live Ovarian Cancer Cells

NaPi2b is a sodium-dependent phosphate transporter that belongs to the SLC34 family of transporters which is mainly responsible for phosphate homeostasis in humans. Although NaPi2b is widely expressed in normal tissues, its overexpression has been demonstrated in ovarian, lung, and other cancers. A...

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Detalles Bibliográficos
Autores principales: Bulatova, Leisan, Savenkova, Daria, Nurgalieva, Alsina, Reshetnikova, Daria, Timonina, Arina, Skripova, Vera, Bogdanov, Mikhail, Kiyamova, Ramziya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335355/
https://www.ncbi.nlm.nih.gov/pubmed/35911971
http://dx.doi.org/10.3389/fmolb.2022.895911