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Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge

BACKGROUND: Crimean-Congo hemorrhagic fever virus is the cause of a severe hemorrhagic fever with cases reported throughout a wide-geographic region. Spread by the bite of infected ticks, contact with infected livestock or in the health care setting, disease begins as a non-specific febrile illness...

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Detalles Bibliográficos
Autores principales: Leventhal, Shanna S., Meade-White, Kimberly, Rao, Deepashri, Haddock, Elaine, Leung, Jacqueline, Scott, Dana, Archer, Jacob, Randall, Samantha, Erasmus, Jesse H., Feldmann, Heinz, Hawman, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335360/
https://www.ncbi.nlm.nih.gov/pubmed/35907368
http://dx.doi.org/10.1016/j.ebiom.2022.104188