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Expanding Biology of PCSK9: Roles in Atherosclerosis and Beyond
PURPOSE OF REVIEW: Since the discovery of PCSK9 in 2003, this proprotein convertase was shown to target specific receptors for degradation in endosomes/lysosomes, including LDLR and other family members and hence to enhance the levels of circulating LDL-cholesterol (LDLc). Accordingly, inhibitors of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335453/ https://www.ncbi.nlm.nih.gov/pubmed/35904732 http://dx.doi.org/10.1007/s11883-022-01057-z |