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Discovery of Leishmania Druggable Serine Proteases by Activity-Based Protein Profiling

Leishmaniasis are a group of diseases caused by parasitic protozoa of the genus Leishmania. Current treatments are limited by difficult administration, high cost, poor efficacy, toxicity, and growing resistance. New agents, with new mechanisms of action, are urgently needed to treat the disease. Alt...

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Detalles Bibliográficos
Autores principales: Porta, Exequiel O. J., Isern, Jaime A., Kalesh, Karunakaran, Steel, Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335491/
https://www.ncbi.nlm.nih.gov/pubmed/35910377
http://dx.doi.org/10.3389/fphar.2022.929493