π-Clamp-Mediated Homo- and Heterodimerization of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation

[Image: see text] Post-translational protein–protein conjugation produces bioconjugates that are unavailable via genetic fusion approaches. A method for preparing protein–protein conjugates using π-clamp-mediated cysteine arylation with pentafluorophenyl sulfonamide functional groups is described. T...

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Detalles Bibliográficos
Autores principales: Taylor, Ross J., Aguilar Rangel, Mauricio, Geeson, Michael B., Sormanni, Pietro, Vendruscolo, Michele, Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335888/
https://www.ncbi.nlm.nih.gov/pubmed/35834748
http://dx.doi.org/10.1021/jacs.2c04747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335888/
https://www.ncbi.nlm.nih.gov/pubmed/35834748
http://dx.doi.org/10.1021/jacs.2c04747

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