Cargando…

Quantifying Biomolecular Interactions Using Slow Mixing Mode (SLOMO) Nanoflow ESI-MS

[Image: see text] Electrospray ionization mass spectrometry (ESI-MS) is a powerful label-free assay for detecting noncovalent biomolecular complexes in vitro and is increasingly used to quantify binding thermochemistry. A common assumption made in ESI-MS affinity measurements is that the relative io...

Descripción completa

Detalles Bibliográficos
Autores principales: Bui, Duong T., Li, Zhixiong, Kitov, Pavel I., Han, Ling, Kitova, Elena N., Fortier, Marlène, Fuselier, Camille, Granger Joly de Boissel, Philippine, Chatenet, David, Doucet, Nicolas, Tompkins, Stephen M., St-Pierre, Yves, Mahal, Lara K., Klassen, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335916/
https://www.ncbi.nlm.nih.gov/pubmed/35912341
http://dx.doi.org/10.1021/acscentsci.2c00215