Tyrosinase-Mediated Synthesis of Nanobody–Cell Conjugates

[Image: see text] A convenient enzymatic strategy is reported for the modification of cell surfaces. Using a tyrosinase enzyme isolated from Agaricus bisporus, unique tyrosine residues introduced at the C-termini of nanobodies can be site-selectively oxidized to reactive o-quinones. These reactive i...

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Detalles Bibliográficos
Autores principales: Maza, Johnathan C., García-Almedina, Derek M., Boike, Lydia E., Hamlish, Noah X., Nomura, Daniel K., Francis, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335918/
https://www.ncbi.nlm.nih.gov/pubmed/35912347
http://dx.doi.org/10.1021/acscentsci.1c01265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335918/
https://www.ncbi.nlm.nih.gov/pubmed/35912347
http://dx.doi.org/10.1021/acscentsci.1c01265

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