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Tyrosinase-Mediated Synthesis of Nanobody–Cell Conjugates
[Image: see text] A convenient enzymatic strategy is reported for the modification of cell surfaces. Using a tyrosinase enzyme isolated from Agaricus bisporus, unique tyrosine residues introduced at the C-termini of nanobodies can be site-selectively oxidized to reactive o-quinones. These reactive i...
Autores principales: | Maza, Johnathan C., García-Almedina, Derek M., Boike, Lydia E., Hamlish, Noah X., Nomura, Daniel K., Francis, Matthew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335918/ https://www.ncbi.nlm.nih.gov/pubmed/35912347 http://dx.doi.org/10.1021/acscentsci.1c01265 |
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