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Oxidative stress-induced premature senescence and aggravated denervated skeletal muscular atrophy by regulating progerin–p53 interaction
BACKGROUND: Progerin elevates atrophic gene expression and helps modify the nuclear membrane to cause severe muscle pathology, which is similar to muscle weakness in the elderly, to alter the development and function of the skeletal muscles. Stress-induced premature senescence (SIPS), a state of cel...
Autores principales: | Xiang, Yaoxian, You, Zongqi, Huang, Xinying, Dai, Junxi, Zhang, Junpeng, Nie, Shuqi, Xu, Lei, Jiang, Junjian, Xu, Jianguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335985/ https://www.ncbi.nlm.nih.gov/pubmed/35906707 http://dx.doi.org/10.1186/s13395-022-00302-y |
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