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Association of childhood BMI trajectory with post-adolescent and adult lung function is mediated by pre-adolescent DNA methylation

BACKGROUND: Body mass index (BMI) has been shown to be associated with lung function. Recent findings showed that DNA methylation (DNAm) variation is likely to be a consequence of changes in BMI. However, whether DNAm mediates the association of BMI with lung function is unknown. We examined the med...

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Detalles Bibliográficos
Autores principales: Rathod, Rutu, Zhang, Hongmei, Karmaus, Wilfried, Ewart, Susan, Mzayek, Fawaz, Arshad, S. Hasan, Holloway, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335987/
https://www.ncbi.nlm.nih.gov/pubmed/35906571
http://dx.doi.org/10.1186/s12931-022-02089-4