A CCR5 antagonist, maraviroc, alleviates neural circuit dysfunction and behavioral disorders induced by prenatal valproate exposure

BACKGROUND: Valproic acid (VPA) is a clinically used antiepileptic drug, but it is associated with a significant risk of a low verbal intelligence quotient (IQ) score, attention-deficit hyperactivity disorder and autism spectrum disorder in children when it is administered during pregnancy. Prenatal...

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Detalles Bibliográficos
Autores principales: Ishihara, Yasuhiro, Honda, Tatsuya, Ishihara, Nami, Namba, Kaede, Taketoshi, Makiko, Tominaga, Yoko, Tsuji, Mayumi, Vogel, Christoph F. A., Yamazaki, Takeshi, Itoh, Kouichi, Tominaga, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335995/
https://www.ncbi.nlm.nih.gov/pubmed/35906621
http://dx.doi.org/10.1186/s12974-022-02559-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335995/
https://www.ncbi.nlm.nih.gov/pubmed/35906621
http://dx.doi.org/10.1186/s12974-022-02559-y

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