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Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia
BACKGROUND: SPG11-linked hereditary spastic paraplegia is characterized by multisystem neurodegeneration leading to a complex clinical and yet incurable phenotype of progressive spasticity and weakness. Severe cognitive symptoms are present in the majority of SPG11 patients, but a systematic and mul...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336101/ https://www.ncbi.nlm.nih.gov/pubmed/35906604 http://dx.doi.org/10.1186/s13023-022-02451-1 |