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Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia

BACKGROUND: SPG11-linked hereditary spastic paraplegia is characterized by multisystem neurodegeneration leading to a complex clinical and yet incurable phenotype of progressive spasticity and weakness. Severe cognitive symptoms are present in the majority of SPG11 patients, but a systematic and mul...

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Detalles Bibliográficos
Autores principales:	Utz, Kathrin S., Kohl, Zacharias, Marterstock, Dominique Cornelius, Doerfler, Arnd, Winkler, Jürgen, Schmidt, Manuel, Regensburger, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336101/ https://www.ncbi.nlm.nih.gov/pubmed/35906604 http://dx.doi.org/10.1186/s13023-022-02451-1

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