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Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease

Demyelination is a common pathological feature of a large number of neurodegenerative diseases including multiple sclerosis and Huntington's disease (HD). Laquinimod (LAQ) has been found to have therapeutic effects on multiple sclerosis and HD. However, the mechanism underlying LAQ's thera...

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Detalles Bibliográficos
Autores principales: Yin, Peng, Liu, Qiong, Pan, Yongcheng, Yang, Weili, Yang, Su, Wei, Wenjie, Chen, Xingxing, Hong, Yan, Bai, Dazhang, Li, Xiao‐Jiang, Li, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336218/
https://www.ncbi.nlm.nih.gov/pubmed/32270922
http://dx.doi.org/10.15252/embr.201949783