Enriched circulating and tumor-resident TGF-β(+) regulatory B cells in patients with melanoma promote FOXP3(+) Tregs

B cells are emerging as key players of anti-tumor adaptive immune responses. We investigated regulatory and pro-inflammatory cytokine-expressing B cells in patients with melanoma by flow cytometric intracellular cytokine, CyTOF, transcriptomic, immunofluorescence, single-cell RNA-seq, and B:T cell c...

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Detalles Bibliográficos
Autores principales: Harris, Robert J, Willsmore, Zena, Laddach, Roman, Crescioli, Silvia, Chauhan, Jitesh, Cheung, Anthony, Black, Anna, Geh, Jenny L. C., MacKenzie Ross, Alastair D, Healy, Ciaran, Tsoka, Sophia, Spicer, James, Lacy, Katie E, Karagiannis, Sophia N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336482/
https://www.ncbi.nlm.nih.gov/pubmed/35909944
http://dx.doi.org/10.1080/2162402X.2022.2104426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336482/
https://www.ncbi.nlm.nih.gov/pubmed/35909944
http://dx.doi.org/10.1080/2162402X.2022.2104426

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