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RNA-binding protein CELF6 modulates transcription and splicing levels of genes associated with tumorigenesis in lung cancer A549 cells

CELF6 (CUGBP Elav-Like Family Member 6), a canonical RNA binding protein (RBP), plays important roles in post-transcriptional regulation of pre-mRNAs. However, the underlying mechanism of lower expressed CELF6 in lung cancer tissues is still unclear. In this study, we increased CELF6 manually in lun...

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Detalles Bibliográficos
Autores principales: Ma, HuSai, Liu, GuoWei, Yu, Bin, Wang, Joshua, Qi, YaLi, Kou, YiYing, Hu, Ying, Wang, ShunJun, Wang, Fei, Chen, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336609/
https://www.ncbi.nlm.nih.gov/pubmed/35910766
http://dx.doi.org/10.7717/peerj.13800