The effect of substance P and its common in vivo‐formed metabolites on MRGPRX2 and human mast cell activation

The tachykinin neuropeptide substance P (SP) is the canonical agonist peptide for the neurokinin 1 receptor (NK(1)R). More recently, it has also been shown to activate the Mas‐related G protein‐coupled receptor X2 (MRGPRX2) receptor on mast cells (MCs), triggering degranulation and release of inflam...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsin, Lin, Fernandopulle, Nithya A., Ding, Jie, Lumb, Chris, Veldhuis, Nicholas, Karas, John A., Northfield, Susan E., Mackay, Graham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337217/
https://www.ncbi.nlm.nih.gov/pubmed/35904495
http://dx.doi.org/10.1002/prp2.990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337217/
https://www.ncbi.nlm.nih.gov/pubmed/35904495
http://dx.doi.org/10.1002/prp2.990

Ejemplares similares