β-arrestin-1 and β-arrestin-2 Restrain MRGPRX2-Triggered Degranulation and ERK1/2 Activation in Human Skin Mast Cells

As a novel receptor that efficiently elicits degranulation upon binding to one of its numerous ligands, MRGPRX2 has moved to the center of attention in mast cell (MC) research. Indeed, MRGPRX2 is believed to be a major component of pseudo-allergic reactions to drugs and of neuropeptide-elicited MC a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhao, Li, Zhuoran, Bal, Gürkan, Franke, Kristin, Zuberbier, Torsten, Babina, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Allergy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337275/
https://www.ncbi.nlm.nih.gov/pubmed/35910860
http://dx.doi.org/10.3389/falgy.2022.930233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337275/
https://www.ncbi.nlm.nih.gov/pubmed/35910860
http://dx.doi.org/10.3389/falgy.2022.930233

Ejemplares similares