7-N-Acetylcysteine-pyrrole conjugate—A potent DNA reactive metabolite of pyrrolizidine alkaloids

Plants containing pyrrolizidine alkaloids (PAs) are widespread throughout the world and are the most common poisonous plants affecting livestock, wildlife, and humans. PAs require metabolic activation to form reactive dehydropyrrolizidine alkaloids (dehydro-PAs) that are capable of alkylating cellul...

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Detalles Bibliográficos
Autores principales: He, Xiaobo, Ma, Liang, Xia, Qingsu, Fu, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337289/
https://www.ncbi.nlm.nih.gov/pubmed/28911605
http://dx.doi.org/10.1016/j.jfda.2016.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337289/
https://www.ncbi.nlm.nih.gov/pubmed/28911605
http://dx.doi.org/10.1016/j.jfda.2016.08.001

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