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Efficacy and safety of ruxolitinib for steroid-refractory graft-versus-host disease: Systematic review and meta-analysis of randomised and non-randomised studies

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) for haematological disorders. Graft-versus-host disease (GVHD), a cause of morbidity and mortality is treated with corticosteroids. However, patients with steroid-refractory GVHD after HSCT have a poor prognosis. Ruxolitinib, a selective Jan...

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Detalles Bibliográficos
Autores principales: Zhang, Meng-yun, Zhao, Peng, Zhang, Yan, Wang, Ji-shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337651/
https://www.ncbi.nlm.nih.gov/pubmed/35905125
http://dx.doi.org/10.1371/journal.pone.0271979