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The selenoprotein P 3’ untranslated region is an RNA binding protein platform that fine tunes selenocysteine incorporation

Selenoproteins contain the 21st amino acid, selenocysteine (Sec), which is incorporated at select UGA codons when a specialized hairpin sequence, the Sec insertion sequence (SECIS) element, is present in the 3’ UTR. Aside from the SECIS, selenoprotein mRNA 3’ UTRs are not conserved between different...

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Detalles Bibliográficos
Autores principales: Shetty, Sumangala P., Kiledjian, Nora T., Copeland, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337670/
https://www.ncbi.nlm.nih.gov/pubmed/35905095
http://dx.doi.org/10.1371/journal.pone.0271453