Modular and hierarchical self-assembly of siRNAs into supramolecular nanomaterials for soft and homogeneous siRNA loading and precise and visualized intracellular delivery

siRNA therapeutics are challenged by homogeneous and efficient loading, maintenance of biological activities, and precise, dynamic and monitorable site-release. Herein, supramolecular nanomaterials of WP5⊃G–siRNA were constructed by modular and hierarchical self-assembly of siRNA with guest (3,6-di(...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Xiaowen, Meng, Fanqi, Tan, Hongwei, Wang, Xiaoni, Li, Jingjing, Wei, Juanjuan, Ouyang, Jin, Na, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337723/
https://www.ncbi.nlm.nih.gov/pubmed/35974751
http://dx.doi.org/10.1039/d2sc02488h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337723/
https://www.ncbi.nlm.nih.gov/pubmed/35974751
http://dx.doi.org/10.1039/d2sc02488h

Ejemplares similares