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N-Methyl deuterated rhodamines for protein labelling in sensitive fluorescence microscopy

Rhodamine fluorophores are setting benchmarks in fluorescence microscopy. Herein, we report the deuterium (d12) congeners of tetramethyl(silicon)rhodamine, obtained by isotopic labelling of the four methyl groups, show improved photophysical parameters (i.e. brightness, lifetimes) and reduced chemic...

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Detalles Bibliográficos
Autores principales: Roßmann, Kilian, Akkaya, Kerem C., Poc, Pascal, Charbonnier, Corentin, Eichhorst, Jenny, Gonschior, Hannes, Valavalkar, Abha, Wendler, Nicolas, Cordes, Thorben, Dietzek-Ivanšić, Benjamin, Jones, Ben, Lehmann, Martin, Broichhagen, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337740/
https://www.ncbi.nlm.nih.gov/pubmed/35974762
http://dx.doi.org/10.1039/d1sc06466e