Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development

Since the ancestors of modern humans separated from those of Neanderthals, around 100 amino acid substitutions spread to essentially all modern humans. The biological significance of these changes is largely unknown. Here, we examine all six such amino acid substitutions in three proteins known to h...

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Detalles Bibliográficos
Autores principales: Mora-Bermúdez, Felipe, Kanis, Philipp, Macak, Dominik, Peters, Jula, Naumann, Ronald, Xing, Lei, Sarov, Mihail, Winkler, Sylke, Oegema, Christina Eugster, Haffner, Christiane, Wimberger, Pauline, Riesenberg, Stephan, Maricic, Tomislav, Huttner, Wieland B., Pääbo, Svante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337762/
https://www.ncbi.nlm.nih.gov/pubmed/35905187
http://dx.doi.org/10.1126/sciadv.abn7702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337762/
https://www.ncbi.nlm.nih.gov/pubmed/35905187
http://dx.doi.org/10.1126/sciadv.abn7702

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