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Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
Since the ancestors of modern humans separated from those of Neanderthals, around 100 amino acid substitutions spread to essentially all modern humans. The biological significance of these changes is largely unknown. Here, we examine all six such amino acid substitutions in three proteins known to h...
Autores principales: | Mora-Bermúdez, Felipe, Kanis, Philipp, Macak, Dominik, Peters, Jula, Naumann, Ronald, Xing, Lei, Sarov, Mihail, Winkler, Sylke, Oegema, Christina Eugster, Haffner, Christiane, Wimberger, Pauline, Riesenberg, Stephan, Maricic, Tomislav, Huttner, Wieland B., Pääbo, Svante |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337762/ https://www.ncbi.nlm.nih.gov/pubmed/35905187 http://dx.doi.org/10.1126/sciadv.abn7702 |
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