Cellular senescence: a key therapeutic target in aging and diseases

Cellular senescence is a hallmark of aging defined by stable exit from the cell cycle in response to cellular damage and stress. Senescent cells (SnCs) can develop a characteristic pathogenic senescence-associated secretory phenotype (SASP) that drives secondary senescence and disrupts tissue homeos...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Pitcher, Louise E., Yousefzadeh, Matthew J., Niedernhofer, Laura J., Robbins, Paul D., Zhu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Review Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337830/
https://www.ncbi.nlm.nih.gov/pubmed/35912854
http://dx.doi.org/10.1172/JCI158450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337830/
https://www.ncbi.nlm.nih.gov/pubmed/35912854
http://dx.doi.org/10.1172/JCI158450

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