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Manganese is a physiologically relevant TORC1 activator in yeast and mammals

The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human diseases. Whether intracellular Mn levels may be sensed and modulate intracellular signaling events has so far remained largely unexplored. The highly conserved target of rapam...

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Detalles Bibliográficos
Autores principales: Nicastro, Raffaele, Gaillard, Hélène, Zarzuela, Laura, Péli-Gulli, Marie-Pierre, Fernández-García, Elisabet, Tomé, Mercedes, García-Rodríguez, Néstor, Durán, Raúl V, De Virgilio, Claudio, Wellinger, Ralf Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337852/
https://www.ncbi.nlm.nih.gov/pubmed/35904415
http://dx.doi.org/10.7554/eLife.80497