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Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice

The inability of neurons to regenerate long axons within the CNS is a major impediment to improving outcome after spinal cord injury, stroke, and other CNS insults. Recent advances have uncovered an intrinsic program that involves coordinate regulation by multiple transcription factors that can be m...

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Detalles Bibliográficos
Autores principales: Cheng, Yuyan, Yin, Yuqin, Zhang, Alice, Bernstein, Alexander M., Kawaguchi, Riki, Gao, Kun, Potter, Kyra, Gilbert, Hui-Ya, Ao, Yan, Ou, Jing, Fricano-Kugler, Catherine J., Goldberg, Jeffrey L., He, Zhigang, Woolf, Clifford J., Sofroniew, Michael V., Benowitz, Larry I., Geschwind, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338053/
https://www.ncbi.nlm.nih.gov/pubmed/35906210
http://dx.doi.org/10.1038/s41467-022-31960-7