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Reducing ether lipids improves Drosophila overnutrition-associated pathophysiology phenotypes via a switch from lipid storage to beta-oxidation

High-calorie diets increase the risk of developing obesity, cardiovascular disease, type-two diabetes (T2D), and other comorbidities. These “overnutrition” diets also promote the accumulation of a variety of harmful lipids in the heart and other peripheral organs, known as lipotoxicity. However, the...

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Detalles Bibliográficos
Autores principales: Santoro, Christie, O’Toole, Ashley, Finsel, Pilar, Alvi, Arsalan, Musselman, Laura Palanker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338069/
https://www.ncbi.nlm.nih.gov/pubmed/35906462
http://dx.doi.org/10.1038/s41598-022-16870-4