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Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction
Oxidative stress and hypoxia in the retinal pigment epithelium (RPE) have long been considered major risk factors in the pathophysiology of age-related macular degeneration (AMD), but systematic investigation of the interplay between these two risk factors was lacking. For this purpose, we treated a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338085/ https://www.ncbi.nlm.nih.gov/pubmed/35906211 http://dx.doi.org/10.1038/s41419-022-05121-z |