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Automated synthesis of [(68)Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

BACKGROUND: The recent development of quinoline-based radiotracers, which act as fibroblast activation protein inhibitors (FAPIs), has shown promising preclinical and clinical advantages. [(68)Ga]Ga-FAPI-46 is a new radiotracer for in vivo detection of the fibroblast activation protein by positron e...

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Detalles Bibliográficos
Autores principales: Alfteimi, Ammar, Lützen, Ulf, Helm, Alexander, Jüptner, Michael, Marx, Marlies, Zhao, Yi, Zuhayra, Maaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338183/
https://www.ncbi.nlm.nih.gov/pubmed/35904684
http://dx.doi.org/10.1186/s41181-022-00172-1