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Preclinical immunogenicity and efficacy of a candidate COVID-19 vaccine based on a vesicular stomatitis virus-SARS-CoV-2 chimera

BACKGROUND: To investigate a vaccine technology with potential to protect against coronavirus disease 2019 (COVID-19) and reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with a single vaccine dose, we developed a SARS-CoV-2 candidate vaccine using the live vesicul...

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Detalles Bibliográficos
Autores principales: Espeseth, Amy S., Yuan, Maoli, Citron, Michael, Reiserova, Lucia, Morrow, Gavin, Wilson, Aaron, Horton, Melanie, Rukhman, Mark, Kinek, Keith, Hou, Fuxiang, Li, Shui L., Li, Fengsheng, Choi, Yesle, Heidecker, Gwen, Luo, Bin, Wu, Guoxin, Zhang, Lan, Strable, Erica, DeStefano, Joanne, Secore, Susan, Mukhopadhyay, Tarit K., Richardson, Douglas D., Sayeed, Eddy, Welch, Lisa S., Bett, Andrew J., Feinberg, Mark B., Gupta, Swati B., Cooper, Christopher L., Parks, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338221/
https://www.ncbi.nlm.nih.gov/pubmed/35915046
http://dx.doi.org/10.1016/j.ebiom.2022.104203