SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model

SARS-CoV-2 variants of concern (VOC) have triggered infection waves. Oral antivirals such as molnupiravir promise to improve disease management, but efficacy against VOC delta was questioned and potency against omicron is unknown. This study evaluates molnupiravir against VOC in human airway epithel...

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Detalles Bibliográficos
Autores principales: Lieber, Carolin M., Cox, Robert M., Sourimant, Julien, Wolf, Josef D., Juergens, Kate, Phung, Quynh, Saindane, Manohar T., Smith, Meghan K., Sticher, Zachary M., Kalykhalov, Alexander A., Natchus, Michael G., Painter, George R., Sakamoto, Kaori, Greninger, Alexander L., Plemper, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338273/
https://www.ncbi.nlm.nih.gov/pubmed/35906230
http://dx.doi.org/10.1038/s41467-022-32045-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338273/
https://www.ncbi.nlm.nih.gov/pubmed/35906230
http://dx.doi.org/10.1038/s41467-022-32045-1

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