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DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomas

Molecular classification has improved diagnosis and treatment for patients with malignant gliomas. However, classification has relied on individual assays that are both costly and slow, leading to frequent delays in treatment. Here, we propose the use of DNA methylation, as an emerging clinical diag...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Wang, Qianghu, Zhang, Ze-Yan, Long, Lihong, Ezhilarasan, Ravesanker, Karp, Jerome M., Tsirigos, Aristotelis, Snuderl, Matija, Wiestler, Benedikt, Wick, Wolfgang, Miao, Yinsen, Huse, Jason T., Sulman, Erik P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338285/
https://www.ncbi.nlm.nih.gov/pubmed/35906213
http://dx.doi.org/10.1038/s41467-022-31827-x