HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Transcriptional regulation by RNA polymerase II is associated with changes in chromatin structure. Activated and promoter-bound heat shock transcription factor 1 (HSF1) recruits transcriptional co-activators, including histone-modifying enzymes; however, the mechanisms underlying chromatin opening r...

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Detalles Bibliográficos
Autores principales: Fujimoto, Mitsuaki, Takii, Ryosuke, Matsumoto, Masaki, Okada, Mariko, Nakayama, Keiich I., Nakato, Ryuichiro, Fujiki, Katsunori, Shirahige, Katsuhiko, Nakai, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338313/
https://www.ncbi.nlm.nih.gov/pubmed/35906200
http://dx.doi.org/10.1038/s41467-022-32034-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338313/
https://www.ncbi.nlm.nih.gov/pubmed/35906200
http://dx.doi.org/10.1038/s41467-022-32034-4

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