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Balanced gene dosage control rather than parental origin underpins genomic imprinting

Mammalian parental imprinting represents an exquisite form of epigenetic control regulating the parent-specific monoallelic expression of genes in clusters. While imprinting perturbations are widely associated with developmental abnormalities, the intricate regional interplay between imprinted genes...

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Detalles Bibliográficos
Autores principales: Weinberg-Shukron, Ariella, Ben-Yair, Raz, Takahashi, Nozomi, Dunjić, Marko, Shtrikman, Alon, Edwards, Carol A., Ferguson-Smith, Anne C., Stelzer, Yonatan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338321/
https://www.ncbi.nlm.nih.gov/pubmed/35906226
http://dx.doi.org/10.1038/s41467-022-32144-z