Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix

BACKGROUND: Induced pluripotent stem cells (iPSCs) have the potential to promote wound healing; however, their adhesion to the extracellular matrix (ECM) might decrease iPSC migration, thereby limiting their therapeutic potential. Integrin β1 (Itgb1) is the major integrin subunit that mediates iPSC-...

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Detalles Bibliográficos
Autores principales: Ren, Yansong, Liu, Jinbo, Xu, Huijun, Wang, Shun, Li, Shirui, Xiang, Meng, Chen, Sifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338467/
https://www.ncbi.nlm.nih.gov/pubmed/35908001
http://dx.doi.org/10.1186/s13287-022-03085-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338467/
https://www.ncbi.nlm.nih.gov/pubmed/35908001
http://dx.doi.org/10.1186/s13287-022-03085-7

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