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Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix

BACKGROUND: Induced pluripotent stem cells (iPSCs) have the potential to promote wound healing; however, their adhesion to the extracellular matrix (ECM) might decrease iPSC migration, thereby limiting their therapeutic potential. Integrin β1 (Itgb1) is the major integrin subunit that mediates iPSC-...

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Detalles Bibliográficos
Autores principales:	Ren, Yansong, Liu, Jinbo, Xu, Huijun, Wang, Shun, Li, Shirui, Xiang, Meng, Chen, Sifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338467/ https://www.ncbi.nlm.nih.gov/pubmed/35908001 http://dx.doi.org/10.1186/s13287-022-03085-7

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